Description
Recombinant Bovine interleukin-1 alpha (IL-1alpha) is a recombinant protein corresponding to aa 120-268 of native bovine IL-1alpha.
Interleukin-1alpha is a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily. It is secreted by activated macrophages and monocytes and is involved in the modulation of a wide range of immune and inflammatory responses.
IL-1alpha and the closely related IL-1beta, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a